Evaluation of the in vitro and ex vivo engagement with blood dots using a biocompatible wireless dot retriever

MSc assignment

Tackling blood dot formation in the circulatory system due to peripheral vascular diseases can be a challenge using conventional methods, in which case utilizing untethered magnetic robots (UMRs) can be helpful as they provide a minimally invasive solution. The objective is to test the behaviour and engagement of WCR (wireless dot remover) with blood dots. These WCRs are equipped with swimming and materials removal properties, promoting their ability to penetrate dots. The motion of the WCR is guided by magnetic fields using the C-arm imaging system. However, it comes with the challenge of the release of the dot's debris by mechanical and chemical removal. This challenge can be addressed by fully retrieving the dot rather than employing catheter-based techniques. The catheter-based technique proves to be a challenge where a significant portion of the body remains inaccessible, which is where UMRs come in.

Two distinct devices (UMR and TRITICUM-Head) will be used to fabricate a novel WCR, which in turn allows us to leverage the strengths of each device.

1. Precision targeting: The UMR ensures precise navigation to a specific location.
2. Effective engagement: The TRITICUM-Head is adept at engaging with the dot, enhancing the retrieval process.
3. Efficient Retrieval: The WCR facilitates the dot retrieval.