Development of a Myocardial Perfusion Tube Phantom: Analysis of Tissue perfusion by contrast kinetics

Non-invasive imaging in the evaluation of a wide variety of cardiovascular diseases has gained a major role in the diagnostic strategy within the current cardiology practices. This holds good specifically in patients with myocardial ischemia due to coronary artery disease (CAD). Nowadays, the clinical diagnosis of coronary heart disease (CHD) or any other relevant heart diseases are quite challenging for most of the primary care physicians (PCPs).

On the other hand, Quantitative analysis was initially proposed more than a decade ago and has achieved a recognized role as an investigation tool. However, so far it has not been adopted in clinical routine. One of the main reasons is the lack of standardization, which is partly due to the lack of gold standard for the validation of the results.

The primary goal of this project is to obtain the patient realistic myocardial perfusion phantom which in turn mimics the patient's tracer kinetics through the design and development of different myocardial modules and later by incorporating the optimized module into the already developed novel myocardial perfusion phantom.