Impact of the orientation of electrodes on IRE parameters

Recently, A non-thermal ablation technique, Irreversible Electroporation (IRE), shown a promising result for treating tumors. IRE utilizes an electric field in the tumor cell membrane via several probes that inserted into the patient body.  Accurate probe placement is essential in this procedure, since misplacement of the probes may leave tumor remains. In this project, the aim is to estimate and optimize the IRE parameter dose, such as the location and the number of electrodes, electric pulse specification, etc.  in order to obtain the desired ablation volume based on the size and shape of the tumor.